Improved antioxidative defence protects insulin-producing cells against homocysteine toxicity
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چکیده
منابع مشابه
Mitochondrial catalase overexpression protects insulin-producing cells against toxicity of reactive oxygen species and proinflammatory cytokines.
Insulin-producing cells are known for their extremely low antioxidant equipment with hydrogen peroxide (H(2)O(2))-inactivating enzymes. Therefore, catalase was stably overexpressed in mitochondria and for comparison in the cytoplasmic compartment of insulin-producing RINm5F cells and analyzed for its protective effect against toxicity of reactive oxygen species (ROS) and proinflammatory cytokin...
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ژورنال
عنوان ژورنال: Chemico-Biological Interactions
سال: 2016
ISSN: 0009-2797
DOI: 10.1016/j.cbi.2016.06.019